Article

Conditional activation of immune-related signatures and prognostic significance: a pan-cancer analysis

2019-02-12

Abstract excerpt

<h4>Background</h4> It is becoming clear that tumor immune T cell infiltration and its functional orientation have substantial effect on cancer progression, influencing both response to therapy and prognosis. In this pan-cancer study, the previously described Immunologic Constant of Rejection (ICR) signature is used to define opposing immune phenotypes (i.e., immuneactive and immune-silent) across 31 different hi...

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Literature Corpus work: 5c438686-4ddc-5f62-bb27-3d35c3dbaa49
DOI: 10.1101/546069

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