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Article

Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response

1 Apr 2020

Abstract excerpt

Background An immune active cancer phenotype typified by a T helper 1 (Th-1) immune response has been associated with increased responsiveness to immunotherapy and favorable prognosis in some but not all cancer types. The reason of this differential prognostic connotation remains unknown. Methods To explore the contextual prognostic value of cancer immune phenotypes, we applied a multimodal pan-cancer analysis...

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PMID: 32376723
DOI: 10.1136/jitc-2020-000617

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