Article

Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery

2024-11-12

Abstract excerpt

The blood-brain barrier (BBB) is a highly specialized system that is critical for regulating transport between the blood and the central nervous system. In brain tumors, the vasculature system is compromised, and is referred to as the blood-tumor barrier (BTB). The ability to precisely model the unique physiological properties of the BTB is essential to decipher its role in tumor pathophysiology and for the ration...

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Literature Corpus work: f09a4581-4bf3-501a-9724-3aeec41f853f
DOI: 10.1101/2024.11.11.622979

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