Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A vascularized tumoroid model for human glioblastoma angiogenesis

1 Oct 2021

Abstract excerpt

Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and stromal surrounds is reported. The model is used to recapitulate how individual components of the GBM's complex brain microenvironment such as hypoxia, vasculature-related stromal cells and growth factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Cancer Cells and Metastasis
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34599235
DOI: 10.1038/s41598-021-98911-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A vascularized tumoroid model for human glioblastoma angiogenesisPMID 34599235Read ↗

Understanding proneural–mesenchymal transition using patient-derived glioma stem-like cell (GSC) organoids and engineered extracellular matrixSemantic proximity Read ↗

3D tumor angiogenesis models: recent advances and challengesSemantic proximity Read ↗

Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic deliverySemantic proximity Read ↗

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene SignaturesSemantic proximity Read ↗

Cancer stem cell-vascular endothelial cell interactions in glioblastoma.Semantic proximity Read ↗

3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of GlioblastomaSemantic proximity Read ↗

Advancing Glioblastoma Research with Innovative Brain Organoid-Based ModelsSemantic proximity Read ↗

Glioma Stem Cells: Signaling, Microenvironment, and TherapySemantic proximity Read ↗

Making a tumour's bed: glioblastoma stem cells and the vascular nicheSemantic proximity Read ↗

CD133+ Glioblastoma Stem-Like Cells Induce Vascular Mimicry in VivoSemantic proximity Read ↗

Modeling Patient-Derived Glioblastoma with Cerebral OrganoidsSemantic proximity Read ↗

Human cortico-vascular assembloids reveal a CELF2-AHNAK-dependent switch from neuronal to endothelial tropism in glioblastoma cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.