Article

A perturbation proteomics-based foundation model for virtual cell construction

2025-02-10

Abstract excerpt

Building a virtual cell requires comprehensive understanding of protein network dynamics of a cell which necessitates large-scale perturbation proteome data and intelligent computational models learned from the proteome data corpus. Here, we generate a large-scale dataset of over 38 million perturbed protein measurements in breast cancer cell lines and develop a neural ordinary differential equation-based foundati...

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Literature Corpus work: 4b8e8d3b-141b-5bb0-b133-e30b594d1a0f
DOI: 10.1101/2025.02.07.637070

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