Article
KSTAR: An algorithm to predict patient-specific kinase activities from phosphoproteomic data
2021-07-08
Abstract excerpt
Kinase inhibitors are one of the largest classes of FDA-approved drugs and are major targets in oncology. Although kinase inhibitors have played an important role in improving cancer outcomes, major challenges still exist, including the development of resistance and failure to respond to treatments. Improvements for tumor profiling of kinase activity would be an important step in improving treatment outcomes and i...
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Identifiers and source
- Literature Corpus work
- d35f6560-e51a-5340-8bc2-93b0e4bc8c84
- DOI
- 10.1101/2021.07.06.451378
