Article

Combined assessment of MHC binding and antigen expression improves T cell epitope predictions

2020-11-10

Abstract excerpt

<h4>ABSTRACT</h4> MHC class I antigen processing consists of multiple steps that result in the presentation of MHC bound peptides that can be recognized as T cell epitopes. Many of the pathway steps can be predicted using computational methods, but one is often neglected: mRNA expression of the epitope source proteins. In this study, we improve epitope prediction by taking into account both peptide-MHC binding af...

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Literature Corpus work: eff9b28c-dbd3-517a-b438-d50dc4becde9
DOI: 10.1101/2020.11.09.375204

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