Article

Flexible machine learning prediction of antigen presentation for rare and common HLA-I alleles

2020-04-25

Abstract excerpt

<h4>Summary</h4> The recent increase of immunopeptidomic data, obtained by mass spectrometry or binding assays, opens unprecedented possibilities for investigating endogenous antigen presentation by the highly polymorphic human leukocyte antigen class I (HLA-I) protein. We introduce a flexible and easily interpretable peptide presentation prediction method, RBM-MHC. We validate its performance as a predictor of c...

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Literature Corpus work: 3f57f439-25c3-5220-b809-1ab839d4c95d
DOI: 10.1101/2020.04.25.061069

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