Article

EPIP: MHC-I epitope prediction integrating mass spectrometry derived motifs and tissue-specific expression profiles

2019-03-05

Abstract excerpt

<h4>Background</h4> Accurate prediction of epitopes presented by human leukocyte antigen (HLA) is crucial for personalized cancer immunotherapies targeting T cell epitopes. Mass spectrometry (MS) profiling of eluted HLA ligands, which provides high-throughput measurements of HLA associated peptides in vivo , can be used to faithfully model the presentation of epitopes on the cell surface. In addition, gene expre...

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Literature Corpus work: 292dee4b-0e2c-55f4-be90-27109dcda7c7
DOI: 10.1101/567081

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