Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone chaperone FACT action during transcription through chromatin by RNA polymerase II.

Proceedings of the National Academy of Sciences of the United States of America - 7 May 2013

Hsieh Fu-Kai, Kulaeva Olga I, Patel Smita S, Dyer Pamela N, Luger Karolin, Reinberg Danny, Studitsky Vasily M

Abstract excerpt

FACT (facilitates chromatin transcription) is a histone chaperone that promotes chromatin recovery during transcription, with additional roles in cell differentiation. Although several models of the action of FACT during transcription have been proposed, they remain to be experimentally evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histones
Share to Chromatin
Share to Cross-Linking Reagents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dimerization

Share to High Mobility Group Proteins

Share to Nucleosomes

Share to RNA Polymerase II

Share to Transcriptional Elongation Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23610384
DOI: 10.1073/pnas.1222198110
PMCID: PMC3651417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23610384-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone chaperone FACT action during transcription through chromatin by RNA polymerase II.PMID 23610384Read ↗

FACT and the reorganized nucleosome.Semantic proximity Read ↗

Integrated molecular mechanism directing nucleosome reorganization by human FACT.Semantic proximity Read ↗

A highly conserved region within H2B is important for FACT to act on nucleosomes.Semantic proximity Read ↗

The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations.Semantic proximity Read ↗

The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts.Semantic proximity Read ↗

The FACT chromatin modulator: genetic and structure/function relationships.Semantic proximity Read ↗

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiationSemantic proximity Read ↗

Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.Semantic proximity Read ↗

Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integrationSemantic proximity Read ↗

Essential histone chaperones collaborate to regulate transcription and chromatin integrity.Semantic proximity Read ↗

FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH.Semantic proximity Read ↗

The FACT histone chaperone guides histone H4 into its nucleosomal conformation in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.