Article

Temporal Stability and Molecular Persistence of the Bone Marrow Plasma Cell Antibody Repertoire

2016-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Plasma cells in human bone marrow (BM PCs) are thought to be intrinsically long-lived and to be responsible for sustaining lifelong immunity through the constitutive secretion of antibody—but the underlying basis for this serological memory remains controversial. Here, we analyzed the molecular persistence of serological immunity by an examination of BM PC immunoglobulin heavy-chain (IGH) transc...

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Literature Corpus work: 7c6ef4a0-4c7f-5659-bd59-f151ce93853e
DOI: 10.1101/066878

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