Article
High-resolution antibody dynamics of vaccine-induced immune responses.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 2014
Laserson Uri, Vigneault Francois, Gadala-Maria Daniel, Yaari Gur, Uduman Mohamed, Vander Heiden Jason A, Kelton William, Taek Jung Sang, Liu Yi, Laserson Jonathan, Chari Raj, Lee Je-Hyuk, Bachelet Ido, Hickey Brendan, Lieberman-Aiden Erez, Hanczaruk Bozena, Simen Birgitte B, Egholm Michael, Koller Daphne, Georgiou George, Kleinstein Steven H, Church George M
Abstract excerpt
The adaptive immune system confers protection by generating a diverse repertoire of antibody receptors that are rapidly expanded and contracted in response to specific targets. Next-generation DNA sequencing now provides the opportunity to survey this complex and vast repertoire. In the present w...
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