Article
Large-scale Analysis of 2,152 dataset reveals key features of B cell biology and the antibody repertoire
2019-10-22
Abstract excerpt
Antibody repertoire sequencing (Ig-seq) has been widely used in studying humoral responses, with promising results. However, the promise of Ig-seq has not yet been fully realized, and key features of the antibody repertoire remain elusive or controversial. To clarify these key features, we analyzed 2,152 high-quality heavy chain antibody repertoires, representing 582 donors and a total of 360 million clones. Our s...
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Identifiers and source
- Literature Corpus work
- 20729738-28eb-5ed8-931b-c69f68126722
- DOI
- 10.1101/814590