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The La Crosse virus class II fusion glycoprotein <i>ij</i> loop contributes to infectivity and cholesterol-dependent entry

2023-02-23

Abstract excerpt

Arthropod-borne viruses (arboviruses) are an emerging and evolving global public health threat with little to no antiviral treatments. La Crosse virus (LACV) from the Bunyavirales order is responsible for pediatric encephalitis cases in the United States, yet little is known about the infectivity of LACV. Given the structural similarities between class II fusion glycoproteins of LACV and chikungunya virus (CHIKV)...

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Literature Corpus work
ef718c26-3f6c-55c3-bfa1-f34975781d5f
DOI
10.1101/2023.02.22.529620
Open publication

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The La Crosse virus class II fusion glycoprotein <i>ij</i> loop contributes to infectivity and cholesterol-dependent entryDOI 10.1101/2023.02.22.529620
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