Article

Deep mutationally scanned (DMS) CHIKV E3/E2 virus library maps viral amino acid preferences and predicts viral escape mutants of neutralizing CHIKV antibodies

2024-12-04

Abstract excerpt

<h4>ABSTRACT</h4> As outbreaks of chikungunya virus (CHIKV), a mosquito-borne alphavirus, continue to present public health challenges, additional research is needed to generate protective and safe vaccines and effective therapeutics. Prior research has established a role for antibodies in mediating protection against CHIKV infection, and the early appearance of CHIKV-specific IgG or IgG neutralizing antibodies p...

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Literature Corpus work: 8aae5008-e508-5234-ba08-28940b2d2135
DOI: 10.1101/2024.12.04.626854

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