Article

A Mathematical Graph-Theoretic Model of Single Point Mutations Associated with Sickle Cell Anemia Disease

2021-09-25

Abstract excerpt

Many diseases like cystic fibrosis and sickle cell anemia disease (SCD), among others, arise from single point mutations in the respective proteins. How a single point mutation might lead to a global devastating consequence on a protein remains an intellectual mystery. SCD is a genetic blood-related disorder resulting from mutations in the beta chain of the human hemoglobin protein (simply, β-globin), subsequently...

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Literature Corpus work: ef710620-c8f3-59a3-8f36-6f20d1e8b456
DOI: 10.24297/jbt.v9i.9109

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