Article

Unraveling the aggregation dynamics of amyloidogenesis: A data-driven mathematical modeling approach

2020-01-06

Abstract excerpt

Proteins often get misfolded into highly ordered amyloid aggregates that are found to be associated with various neurodegenerative diseases. However, the dynamical events that lead to such self organization of different types of proteins are still poorly understood due to the experimentally untractable complex molecular mechanism, which governs the process of amyloidogenesis. Herein, we propose a generic and data-...

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Literature Corpus work: 5e16796c-5540-5118-8c5d-ce8a0015e2f8
DOI: 10.1101/2020.01.06.895649

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