Analysis of functional aberration of some important beta hemoglobinopathies (hemoglobin C, D, E, and S) from nanostructures.

Abstract excerpt

Hemoglobinopathy comprises a group of inherited hemoglobin disorders in which hemoglobin (Hb) was improperly formed, but the cause is not depletion of the globin gene. Typically, when the basic pathogenesis is a single substitution disorder, only one aberration presents in the secondary structure. However, the manifested or functional aberration resulting from the structural aberration usually varies. It is...

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