Article

Targeted Modification of the Foot-And-Mouth Disease Virus Genome for Quick Cell Culture Adaptation

2020-08-31

Abstract excerpt

Foot-and-mouth disease virus (FMDV) causes the highly contagious foot-and-mouth disease, which is characterized by the appearance of vesicles in and around the mouth and feet of cloven-hoofed animals. BHK21 cells are the cell line of choice for the propagation of FMDV for vaccine production world-wide but vary in their susceptibility for different FMDV strains. Previous studies showed that the FMDV resistance of a...

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Literature Corpus work: ef12fc35-194d-5f13-af76-e983efd20ced
DOI: 10.20944/preprints202008.0712.v1

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