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Article

Mutation in the 1D gene (VP1) of Foot-and-mouth disease virus serotype Asia1 during serial cytolytic infections in cell culture.

Archives of virology - 1 Sept 2003

Manoj Kumar R, Sanyal A, Tosh C, Hemadri D, Mohapatra J K, Venkataramanan R, Bandyopadhyay S K

Abstract excerpt

Changes in the nucleotide sequence of the 1D gene of two vaccine strains (IND 63/72 and IND 491/97) of Foot-and-mouth disease virus (FMDV) serotype Asia1 during serial cytolytic infections in cell culture have been analyzed. Sequence comparisons revealed a majority of transition mutations in IND 491/97. The mutation frequency of the 1D gene of IND 491/97 was about 4.5 to 6.0 fold higher than that of IND 63/72. At...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Capsid Proteins
Cells, Cultured
Epitopes
Foot-and-Mouth Disease Virus
Molecular Sequence Data
Mutation
Serotyping
Structure-Activity Relationship

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Identifiers

PMID: 14505092
DOI: 10.1007/s00705-003-0135-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14505092-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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