Article
Influence of cell type and cell culture media on the propagation of foot-and-mouth disease virus with regard to vaccine quality.
Virology journal - 16 Mar 2018
Dill Veronika, Hoffmann Bernd, Zimmer Aline, Beer Martin, Eschbaumer Michael
Abstract excerpt
BACKGROUND: Suspension culture of BHK cells allows large-scale virus propagation and cost-efficient vaccine production, while the shift to animal-component-free cell culture media without serum is beneficial for the quality and downstream processing of the product. Foot-and-mouth disease virus is still endemic in many parts of the world and high-quality vaccines are essential for the eradication of this highly...
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