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Article

The VP1 S154D mutation of type Asia1 foot-and-mouth disease virus enhances viral replication and pathogenicity.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2016

Lian Kaiqi, Yang Fan, Zhu Zixiang, Cao Weijun, Jin Ye, Liu Huanan, Li Dan, Zhang Keshan, Guo Jianhong, Liu Xiangtao, Zheng Haixue

Abstract excerpt

One of the proteins encoded by the foot-and-mouth disease virus (FMDV), the VP1 protein, a capsid protein, plays an important role in integrin receptor attachment and humoral immunity-mediated host responses. The integrin receptor recognition motif and an important antigenic epitope exist within the G-H loop, which is comprised of amino acids 134-160 of the VP1 protein. FMDV strain, Asia1/HN/CHA/06, isolated from...

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Identifiers

PMID: 26792712
DOI: 10.1016/j.meegid.2016.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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