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Article

Propagation of an attenuated virus by design: engineering a novel receptor for a noninfectious foot-and-mouth disease virus.

17 Sept 1996

Abstract excerpt

To gain entry into cells, viruses utilize a variety of different cell-surface molecules. Foot-and-mouth disease virus (FMDV) binds to cell-surface integrin molecules via an arginine-glycine-aspartic acid (RGD) sequence in capsid protein VP1. Binding to this particular cell-surface molecule influences FMDV tropism, and virus/receptor interactions appear to be responsible, in part, for selection of antigenic...

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Identifiers

PMID: 8816817
DOI: 10.1073/pnas.93.19.10428

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Propagation of an attenuated virus by design: engineering a novel receptor for a noninfectious foot-and-mouth disease virus.PMID 8816817Read ↗

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