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Interrogating the complex relationship between Alzheimer’s disease and blood pressure: two instrumental variable approaches to focus on pre-clinical stages of Alzheimer’s disease in UK Biobank

2024-10-17

Abstract excerpt

<h4>Background and Aims</h4> Evidence suggests there may be a bidirectional relationship between high blood pressure (BP) and Alzheimer’s disease (AD). It is hypothesised that this is due to cerebral changes during pre-clinical AD that cause elevation of systemic BP. We aimed to test this by exploring the effect of risk of pre-clinical AD on blood pressure. <h4>Methods</h4> We used data from the UK Biobank, includ...

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Literature Corpus work: eee8ee2b-e900-5861-8882-bb98a2f9ea0d
DOI: 10.1101/2024.10.17.24315654

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