Article

High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay

2019-04-18

Abstract excerpt

Antibodies raised against defined phosphorylation sites of the microtubule-associated protein tau are widely used in scientific research and being applied in clinical assays. However, recent studies have revealed an alarming degree of non-specific binding found in these antibodies. In order to quantify and compare the specificity phospho-tau antibodies and other post-translational modification site-specific antibo...

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Literature Corpus work: eed1841c-f050-5c6e-a852-6fa0de927590
DOI: 10.1101/612911

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