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Integrative mediation and multi-omics analysis to decode Aortic dissection’s genetic causal phenotype and potential therapeutic targets

2025-06-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Aortic dissection(AD) is a fatal cardiovascular emergency associated with inflammation, immunity, and metabolic factors. Understanding the underlying etiology and identifying pathogenic targets of AD is essential for its prevention, accurate diagnosis, and effective treatment. <h4>Objective:</h4> We sought to elucidate the mediating role of metabolites in the cau...

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Literature Corpus work
fc7789f5-3430-5670-a9dd-3a60d108c75d
DOI
10.21203/rs.3.rs-6680735/v1
Open publication

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Integrative mediation and multi-omics analysis to decode Aortic dissection’s genetic causal phenotype and potential therapeutic targetsDOI 10.21203/rs.3.rs-6680735/v1
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