Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of HMGB1 and its associated signaling pathways in human malignancies

25 Sept 2023

Abstract excerpt

The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 has been reported to regulate several signaling pathways engaged in inflammation, genome stability, immune function, cell proliferation, cell autophagy, metabolism, and apoptosis. However, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Cholesterol and Lipid Metabolism
Share to Natural Antidiabetic Agents Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37757902
DOI: 10.1016/j.cellsig.2023.110904

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of HMGB1 and its associated signaling pathways in human malignanciesPMID 37757902Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

Emerging roles for HMGB1 protein in immunity, inflammation, and cancerSemantic proximity Read ↗

The dual role and therapeutic potential of high-mobility group box 1 in cancerSemantic proximity Read ↗

HMGA1 in cancer: Cancer classification by locationSemantic proximity Read ↗

High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity Read ↗

High Mobility Group Box 1 in Human CancerSemantic proximity Read ↗

Masquerader: High Mobility Group Box-1 and CancerSemantic proximity Read ↗

HMGB1: An overview of its roles in the pathogenesis of liver diseaseSemantic proximity Read ↗

Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine functionSemantic proximity Read ↗

High-mobility group box-1 and its role in angiogenesisSemantic proximity Read ↗

HMGB1: a double-edged sword and therapeutic target in the female reproductive systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.