Article
HMG chromosomal proteins in development and disease.
Trends in cell biology - 1 Feb 2007
Hock Robert, Furusawa Takashi, Ueda Tetsuya, Bustin Michael
Abstract excerpt
The high mobility group (HMG) proteins are a superfamily of abundant and ubiquitous nuclear proteins that bind to DNA and nucleosomes and induce structural changes in the chromatin fiber. They are important in chromatin dynamics and influence DNA processing in the context of chromatin. Results emerging from studies of human disease, genetically modified mice and cells with altered HMG expression indicate that the...
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