Article

Maturation of Purkinje cell firing properties relies on granule cell neurogenesis

2020-05-23

Abstract excerpt

<h4>SUMMARY</h4> Preterm infants that suffer cerebellar insults often develop motor disorders and cognitive difficulty. Granule cells are especially vulnerable, and they likely instigate disease by impairing the function of Purkinje cells. Here, we use regional genetic manipulations and in vivo electrophysiology to test whether granule cells help establish the firing properties of Purkinje cells during postnatal...

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Literature Corpus work: 69a450b3-9386-550a-8086-ce91f9df566f
DOI: 10.1101/2020.05.20.106732

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