Article

Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types

2018-09-03

Abstract excerpt

Microsatellites are repeats of 1-6bp units and ∼10 million microsatellites have been identified across the human genome. Microsatellites are vulnerable to DNA mismatch errors, and have thus been used to detect cancers with mismatch repair deficiency. To reveal the mutational landscape of the microsatellite repeat regions at the genome level, we analyzed approximately 20.1 billion microsatellites in 2,717 whole gen...

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Literature Corpus work: edbad7bb-e8ea-552c-aa1a-46c1e7512e59
DOI: 10.1101/406975

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