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Article

Microsatellite instability in the development of DNA mismatch repair deficient tumors

21 Jun 2006

Abstract excerpt

Microsatellites are highly abundant short repetitive sequences found in the genomes across different species. They have gained increasing interest in recent years because length alterations in several coding as well as non-coding microsatellites are associated with a variety of different disorders. Particularly, microsatellite mutations play an important role in tumorigenesis of DNA mismatch repair deficient...

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PMID: 17192061
DOI: 10.3233/cbm-2006-21-208

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