Article

NHJ-1 regulates canonical non-homologous end joining in <i>Caenorhabditis elegans</i>

2019-09-09

Abstract excerpt

Canonical non-homologous end joining (cNHEJ) is a near-universally conserved pathway for the repair of DNA double-strand breaks (DSBs). While the cNHEJ pathway encompasses more than a dozen factors in vertebrates and is similarly complex in other eukaryotes, in the nematode C. elegans the entire known cNHEJ toolkit consists of two proteins that comprise the Ku ring complex, cku-70 and cku-80 , and the terminal...

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Literature Corpus work: ed948a11-299e-5900-a30a-6868d55c00af
DOI: 10.1101/763235

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