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Article

Developmental modulation of nonhomologous end joining in Caenorhabditis elegans.

Genetics - 1 Jul 2006

Clejan Iuval, Boerckel Julie, Ahmed Shawn

Abstract excerpt

Homologous recombination and nonhomologous end joining (NHEJ) are important DNA double-strand break repair pathways in many organisms. C. elegans strains harboring mutations in the cku-70, cku-80, or lig-4 NHEJ genes displayed multiple developmental abnormalities in response to radiation-induced DNA damage in noncycling somatic cells. These phenotypes did not result from S-phase, DNA damage, or mitotic...

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Identifiers

PMID: 16702421
DOI: 10.1534/genetics.106.058628
PMCID: PMC1526663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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