Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NHJ-1 Is Required for Canonical Nonhomologous End Joining in Caenorhabditis elegans.

Genetics - 1 Jul 2020

Vujin Aleksandar, Jones Steven J, Zetka Monique

Abstract excerpt

DNA double-strand breaks (DSBs) are a particularly lethal form of DNA damage that must be repaired to restore genomic integrity. Canonical nonhomologous end joining (NHEJ), is a widely conserved pathway that detects and directly ligates the broken ends to repair the DSB. These events globally require the two proteins that form the Ku ring complex, Ku70 and Ku80, and the terminal ligase LIG4. While the NHEJ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA End-Joining Repair

Share to Mutation

Share to Radiation, Ionizing

Source

Open in PubMed Open full text

Identifiers

PMID: 32457132
DOI: 10.1534/genetics.120.303328
PMCID: PMC7337088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NHJ-1 Is Required for Canonical Nonhomologous End Joining in Caenorhabditis elegans.PMID 32457132Read ↗

NHJ-1 regulates canonical non-homologous end joining in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Developmental modulation of nonhomologous end joining in Caenorhabditis elegans.Semantic proximity Read ↗

Interdependent and separable functions of <i>C. elegans</i> MRN-C complex members couple formation and repair of meiotic DSBsSemantic proximity Read ↗

EYA-1 is required for genomic integrity independent of H2AX signalling in Caenorhabditis elegans.Semantic proximity Read ↗

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.Semantic proximity Read ↗

EYA-1 is required for genomic integrity independent of H2AX signalling in Caenorhabditis elegansSemantic proximity Read ↗

X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1.Semantic proximity Read ↗

Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.Semantic proximity Read ↗

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases.Semantic proximity Read ↗

Transgenerational inheritance of paternal DNA damage by linker histone H1-mediated DNA repair restrictionSemantic proximity Read ↗

Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates.Semantic proximity Read ↗

Caenorhabditis elegans DNA-2 helicase/endonuclease plays a vital role in maintaining genome stability, morphogenesis, and life span.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.