Article

PROPEL: a high-throughput shear-stress platform reveals organotypic thresholds in endothelial mechano-adaptation

2026-07-23

Abstract excerpt

Endothelial cells exhibit organotypic specialization, yet the tools to decode whether hemodynamic shear shapes this diversity across vascular beds have remained limited. Here we present PROPEL, a tubing-free, magnetic stirrer-driven platform that delivers programmable laminar shear stress (2 to 60 dyn/cm 2 ) to multiple cell types in parallel within the confines of a standard Petri dish, with the modular flexibil...

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Literature Corpus work: ed787daa-8299-5882-9f88-7bc971114011
DOI: 10.64898/2026.07.22.740104

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