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Fluid Mechanics, Arterial Disease, and Gene Expression

11 Oct 2013

Abstract excerpt

This review places modern research developments in vascular mechanobiology in the context of hemodynamic phenomena in the cardiovascular system and the discrete localization of vascular disease. The modern origins of this field are traced, beginning in the 1960s when associations between flow characteristics, particularly blood flow-induced wall shear stress, and the localization of atherosclerotic plaques were...

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PMID: 25360054
DOI: 10.1146/annurev-fluid-010313-141309

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