Article

Endothelial Cell Polarization and Orientation to Flow in a Novel Microfluidic Multimodal Shear Stress Generator

2020-07-10

Abstract excerpt

Endothelial cells (EC) respond to shear stress to maintain vascular homeostasis, and a disrupted response is associated with cardiovascular diseases. To understand how different shear stress modalities affect EC morphology and behavior, we developed a microfluidic device that concurrently generates three different levels of uniform wall shear stress (WSS) and six different WSS gradients (WSSG). In this device, hum...

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Literature Corpus work: 85cb80f7-41e1-5b92-9272-bf06e65eb83c
DOI: 10.1101/2020.07.10.197244

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