Article
Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia
2021-04-16
Abstract excerpt
Despite the extensive catalogue of recurrent mutations in chronic lymphocytic leukaemia (CLL), the diverse molecular driving events and the resulting range of disease phenotypes remain incompletely understood. To study the molecular heterogeneity of CLL, we performed RNA-sequencing on 184 CLL patient samples. Unsupervised analysis revealed two major independent axes of gene expression variation: the first one alig...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- ed44c28f-4549-5844-8565-ffd08bc9ed88
- DOI
- 10.1101/2021.04.16.440134