Article
Genomic and Epigenomic Alterations in Chronic Lymphocytic Leukemia.
Annual review of pathology - 24 Jan 2020
Nadeu Ferran, Diaz-Navarro Ander, Delgado Julio, Puente Xose S, Campo Elías
Abstract excerpt
Chronic lymphocytic leukemia is a common disease in Western countries and has heterogeneous clinical behavior. The relevance of the genetic basis of the disease has come to the forefront recently, with genome-wide studies that have provided a comprehensive view of structural variants, somatic mutations, and different layers of epigenetic changes. The mutational landscape is characterized by relatively common copy...
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