Article

Insulin-like growth factor-1 (IGF-1), insulin-like growth factor-binding protein-3 (IGFBP-3) and breast cancer risk: observational and Mendelian randomization analyses

2019-10-24

Abstract excerpt

<h4>Background</h4> Epidemiological evidence supports a positive association between circulating insulin-like growth factor-1 (IGF-1) concentrations and breast cancer risk, but both the magnitude and causality of this relationship are uncertain. We conducted observational analyses with adjustment for regression dilution bias, and Mendelian randomization (MR) analyses to allow causal inference. <h4>Patients and me...

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Literature Corpus work: ed09ccf7-bfa8-55e8-bd30-32a031dc578a
DOI: 10.1101/809046

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