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Article

Causal inference study of the effect of serum enzymes on breast cancer risk: Two-sample Mendelian randomization.

Medicine - 26 Jun 2026

Zhao Liying, Zeng Cheng, Jia Xiaohui, Cui Keliang, Wang Jiani, Xia Bing

Abstract excerpt

Breast cancer (BC) has the highest cancer incidence and mortality in women worldwide, and the relationship between serum enzymes and BC has been inconsistent in previous observational studies. In this paper, 2-sample Mendelian randomization (MR) is used to clarify the causal relationship between them. The serum enzymes in 216,026 study subjects from Finnish heritage subjects as the exposure data. The BC included...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42363553
DOI: 10.1097/MD.0000000000049516
PMCID: PMC13313707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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