Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study.

Cancer medicine - 1 Sept 2020

Larsson Susanna C, Carter Paul, Vithayathil Mathew, Kar Siddhartha, Mason Amy M, Burgess Stephen

Abstract excerpt

Insulin-like growth factor-1 (IGF-1) is involved in several processes relevant to carcinogenesis. We used 416 single-nucleotide polymorphisms robustly associated with serum IGF-1 levels to assess the potential causal associations between this hormone and site-specific cancers through Mendelian randomization. Summary-level genetic association estimates for prostate, breast, ovarian, and lung cancer were obtained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Europe
Share to Insulin-Like Growth Factor I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Risk Assessment

Share to Up-Regulation

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 32717139
DOI: 10.1002/cam4.3345
PMCID: PMC7520358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study.PMID 32717139Read ↗

Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation studySemantic proximity Read ↗

Blood Lipid Metabolic Profiles and Causal Links to Site-Specific Cancer Risks: A Mendelian Randomization Study.Semantic proximity Read ↗

Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysisSemantic proximity Read ↗

Causal effects of blood and urinary biomarkers on cancer risk: A Mendelian randomization study.Semantic proximity Read ↗

Vitamin D and overall cancer risk and cancer mortality: a Mendelian randomization studySemantic proximity Read ↗

Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.Semantic proximity Read ↗

Body Mass Index and Risk of Female Reproductive System Tumors Subtypes: A Meta-Analysis Using Mendelian Randomization.Semantic proximity Read ↗

35 blood and urine biomarkers and digestive system cancers: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Effect of Basal Metabolic Rate on Cancer: A Mendelian Randomization StudySemantic proximity Read ↗

Body fatness associations with cancer: evidence from recent epidemiological studies and future directionsSemantic proximity Read ↗

Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Insulin-like growth factor-1 (IGF-1), insulin-like growth factor-binding protein-3 (IGFBP-3) and breast cancer risk: observational and Mendelian randomization analysesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.