Article

Predicting trait regulators by identifying co-localization of DNA binding and GWAS variants in regulatory regions

2018-11-11

Abstract excerpt

Genomic regions associated with complex traits and diseases are primarily located in non-coding regions of the genome and have unknown mechanism of action. A critical step to understanding the genetics of complex traits is to fine-map each associated locus; that is, to find the causal variant(s) that underlie genetic associations with a trait. Fine-mapping approaches are currently focused on identifying genomic an...

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Literature Corpus work: ed01279c-96b4-5f47-8a75-6cf0a582dcb5
DOI: 10.1101/467852

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