Article

Modeling tissue-resident macrophage development from mouse pluripotent stem cells

2025-05-05

Abstract excerpt

<h4>SUMMARY</h4> Tissue-resident macrophages (TRMs) are innate immune cells that participate in tissue development, homeostasis, and immune surveillance. Extensive efforts have been made to recapitulate TRM development from pluripotent stem cells (PSCs) in vitro to study molecular and cellular mechanisms of TRM development and to create cellular models of disease. However, available PSC models of mouse TRM deve...

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Literature Corpus work: ecadcb10-7819-57be-aaaa-5475599fa8f3
DOI: 10.1101/2025.05.01.651743

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