Article
Production and Characterization of Human Macrophages from Pluripotent Stem Cells.
Journal of visualized experiments : JoVE - 16 Apr 2020
Lopez-Yrigoyen Martha, May Alisha, Ventura Telma, Taylor Helen, Fidanza Antonella, Cassetta Luca, Pollard Jeffrey W, Forrester Lesley M
Abstract excerpt
Macrophages are present in most vertebrate tissues and comprise widely dispersed and heterogeneous cell populations with different functions. They are key players in health and disease, acting as phagocytes during immune defense and mediating trophic, maintenance, and repair functions. Although it has been possible to study some of the molecular processes involved in human macrophage function, it has proved...
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