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Production and Characterization of Human Macrophages from Pluripotent Stem Cells.

Journal of visualized experiments : JoVE - 16 Apr 2020

Lopez-Yrigoyen Martha, May Alisha, Ventura Telma, Taylor Helen, Fidanza Antonella, Cassetta Luca, Pollard Jeffrey W, Forrester Lesley M

Abstract excerpt

Macrophages are present in most vertebrate tissues and comprise widely dispersed and heterogeneous cell populations with different functions. They are key players in health and disease, acting as phagocytes during immune defense and mediating trophic, maintenance, and repair functions. Although it has been possible to study some of the molecular processes involved in human macrophage function, it has proved...

Topics

Biomarkers
Cell Count
Cell Culture Techniques
Cell Differentiation
Cell Membrane
Cell Polarity
Cell Shape
Cells, Cultured
Embryoid Bodies
Humans
Induced Pluripotent Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages

Phagocytosis

Phenotype

Source

Identifiers

PMID: 32364544
DOI: 10.3791/61038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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