Article
Human Induced Pluripotent Stem Cell-Derived Macrophages for Unraveling Human Macrophage Biology.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017
Zhang Hanrui, Reilly Muredach P
Abstract excerpt
Despite a substantial appreciation for the critical role of macrophages in cardiometabolic diseases, understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies. Human induced pluripotent stem cell (iPSC)-derived macrophages (IPSDM), as an unlimited source of subject genotype-specific cells, will undoubtedly play an important role in...
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