Article

Nutrient restriction, inducer of yeast meiosis, induces meiotic initiation in mammals

2020-05-16

Abstract excerpt

<h4>ABSTRACT</h4> From yeasts to mammals, the molecular machinery and chromosome structures carrying out meiosis are frequently conserved. However, the signal to initiate meiosis appears divergent: while nutrient restriction induces meiosis in the yeast system, retinoic acid (RA), a chordate morphogen, is necessary but not sufficient to induce meiotic initiation in mammalian germ cells via its target, Stra8 . He...

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Literature Corpus work: ec91f918-fd1b-5643-89ad-8e543376739e
DOI: 10.1101/2020.05.15.074542

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