Article

Integrated epigenome and transcriptome analysis of normal and arrested meiotic initiation during mouse spermatogenesis

2022-02-19

Abstract excerpt

The transition from mitotic to meiotic cell cycles is a transcriptional event that entails the activation of genes important for meiosis and requires germline-specific retinoic acid (RA) signaling target, Stra8 . To identify novel transcription factors underlying mammalian meiotic initiation, we conducted integrative snATAC-seq and scRNA-seq analysis using wild-type and Stra8 -deficient mouse testicular cells to...

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Literature Corpus work: a5f3fdf0-f430-5ba4-85b4-04fbae789e0d
DOI: 10.1101/2022.02.18.481086

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