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Identification and Expression of Potential Regulators of the Mammalian Mitotic-to-Meiotic Transition1

9 Sept 2010

Abstract excerpt

Meiosis is unique to germ cells and occurs in a sex-specific manner. The genes regulating meiotic initiation in either sex are yet to be fully elucidated. Recent studies have revealed the importance of retinoic acid and one of its target genes, Stra8, in meiotic initiation in both sexes. Microarray analysis of whole murine embryonic ovary and postnatal testis time course data revealed a single peak of Stra8...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 20826732
DOI: 10.1095/biolreprod.110.086215

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