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Article

Regulation of meiotic entry and gonadal sex differentiation in the human: normal and disrupted signaling

24 Jun 2014

Abstract excerpt

Meiosis is a unique type of cell division that is performed only by germ cells to form haploid gametes. The switch from mitosis to meiosis exhibits a distinct sex-specific difference in timing, with female germ cells entering meiosis during fetal development and male germ cells at puberty when spermatogenesis is initiated. During early fetal development, bipotential primordial germ cells migrate to the forming...

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PMID: 25372763
DOI: 10.1515/bmc-2014-0014

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